SCHEMBL9974709

SCHEMBL9974709

CC(=O)c1ccc(C(=O)I)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.56
RAB9A P51151 5/20 0.56
HPGD P15428 4/20 0.56
KMT2A Q03164 3/20 0.56
LMNA P02545 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
SMN1; SMN2 Q16637 4/20 0.54
HSD17B1 P14061 1/20 0.54
MAPK1 P28482 2/20 0.50
NOS3 P29474 2/20 0.50
NOS1 P29475 2/20 0.50
NPC1 O15118 4/20 0.48
MEN1 O00255 1/20 0.48
HTT P42858 1/20 0.48
NLRP1 Q9C000 1/20 0.48
ALDH1A1 P00352 1/20 0.48
STAT3 P40763 1/20 0.48
STAT1 P42224 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19730946 0.92 MAPT (0.67) MAPTRAB9AHPGDKMT2ALMNA
SCHEMBL50646 0.87 MAPT (0.68) MAPTRAB9AHPGDKMT2ALMNA
SCHEMBL815029 0.84 TSHR (0.50) MAPTHPGDLMNAHTTALDH1A1
Benzene SCHEMBL5533098 0.81 MAPT (0.75) MAPTRAB9AHPGDKMT2ALMNA
Acetic Acid SCHEMBL28009208 0.81 MAPT (0.67) MAPTRAB9AHPGDKMT2ALMNA
SCHEMBL17187946 0.80 MAPT (0.69) MAPTRAB9AHPGDKMT2ALMNA
SCHEMBL457196 0.80 TPMT (0.59) MAPTRAB9AHPGDKMT2ALMNA
SCHEMBL17187843 0.80 TPMT (0.59) MAPTRAB9AHPGDKMT2ALMNA
SCHEMBL75640 0.80 MAPT (0.69) MAPTRAB9AHPGDKMT2ALMNA
SCHEMBL28193245 0.80 MAPT (0.69) MAPTRAB9AHPGDKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11781013-B2 Thermoplastic composites and corresponding fabrication methods and articles SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-10-10 US disclosed
US-10689489-B2 Polyimide-based block copolymer and polyimide-based film comprising the same LG CHEM LTD. (KR) 2020-06-23 US disclosed
US-20200131315-A1 POLYAMIDE-IMIDE RESIN FILM LG CHEM, LTD. (KR) 2020-04-30 US disclosed
US-20190315925-A1 POLYIMIDE-BASED COPOLYMER AND POLYIMIDE-BASED FILM COMPRISING THE SAME LG CHEM, LTD. (KR) 2019-10-17 US disclosed
US-20170166952-A1 Polymer-Based Signal Amplification for Protein and Cell Detection THE PENN STATE RESEARCH FOUNDATION 2017-06-15 US disclosed
WO-2012082837-A1 METHOD OF MAKING INDENO-FUSED NAPHTHOL MATERIALS TRANSITIONS OPTICAL, INC. (US) 2012-06-21 WO disclosed
US-8202674-B2 Polymers of napthalene tetracarboxylic diimide dimers XEROX CORPORATION (US) 2012-06-19 US disclosed
WO-2011053615-A1 PHOTOCHROMIC MATERIALS TRANSITIONS OPTICAL, INC. (US) 2011-05-05 WO disclosed
US-20110028724-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS XEROX CORPORATION (US) 2011-02-03 US disclosed
US-7449268-B2 Polycarbonates, polyesters and polyimides from the dimers exhibit properties of both binders and an electron-transporting materials; electrographic and photoconductor elements XEROX CORPORATION (US) 2008-11-11 US disclosed
WO-2008054942-A2 PHOTOCHROMIC MATERIALS DEMONSTRATING IMPROVED FADE RATES TRANSITIONS OPTICAL, INC. (US) 2008-05-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028724-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS SLC43A3, SLC29A1, SLCO1A2 MAPT 318/4885RAB9A 3023/4885HPGD 567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.