Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34001 | 0.89 | KCNH2 (0.35) | KCNH2MAP4K4HRH1CHRM1PIM1 | |
| Hydrochloric Acid SCHEMBL2929557 | 0.88 | KCNH2 (0.35) | KCNH2MAP4K4HRH1CHRM1PIM1 | |
| SCHEMBL18975358 | 0.85 | MAP4K4 (0.37) | KCNH2MAP4K4HRH1CHRM1PIM1 | |
| SCHEMBL3138328 | 0.85 | MAP4K4 (0.35) | KCNH2MAP4K4PIM1PIM3PIM2 | |
| SCHEMBL10325917 | 0.76 | KCNH2 (0.33) | KCNH2MAP4K4HRH1CHRM1PIM1 | |
| SCHEMBL3138338 | 0.73 | HRH4 (0.34) | KCNH2MAP4K4PIM1PIM3PIM2 | |
| SCHEMBL20798578 | 0.72 | PDGFRB (0.38) | KCNH2MAP4K4HRH1CHRM1PIM1 | |
| SCHEMBL943802 | 0.70 | IKBKB (0.35) | — | |
| SCHEMBL28213063 | 0.64 | MAP4K4 (0.34) | KCNH2MAP4K4HRH1CHRM1HRH3 | |
| SCHEMBL684126 | 0.62 | HRH3 (0.41) | HRH1HRH3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080289-A2 | DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |