Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34001 | 0.95 | KCNH2 (0.35) | MAP4K4HRH4HRH3MCHR1KCNH2 | |
| Hydrochloric Acid SCHEMBL2929557 | 0.94 | KCNH2 (0.35) | MAP4K4HRH4HRH3MCHR1KCNH2 | |
| SCHEMBL3138338 | 0.86 | HRH4 (0.34) | MAP4K4HRH4HRH3MCHR1KCNH2 | |
| SCHEMBL9974728 | 0.85 | KCNH2 (0.34) | MAP4K4HRH4HRH3KCNH2PIM1 | |
| Hydrochloric Acid SCHEMBL3932856 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL10325917 | 0.79 | KCNH2 (0.33) | MAP4K4HRH4HRH3MCHR1KCNH2 | |
| SCHEMBL943802 | 0.76 | IKBKB (0.35) | — | |
| SCHEMBL18975358 | 0.74 | MAP4K4 (0.37) | MAP4K4HRH4HRH3MCHR1KCNH2 | |
| SCHEMBL15651890 | 0.72 | — | — | |
| SCHEMBL20798578 | 0.68 | PDGFRB (0.38) | MAP4K4HRH4HRH3MCHR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2198831-A1 | Method for lightening, lightening direct dyeing or oxidation dyeing carried out in the presence of an organic amine and a mineral base; suitable kit | L'Oreal (FR) | 2010-06-23 | — | — | EP | disclosed |