Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997493 | 1.00 | DPP7 (0.47) | DPP7SLC6A3SLC6A2LMNAGAA | |
| SCHEMBL998428 | 0.98 | DPP7 (0.50) | DPP7SLC6A3SLC6A2LMNAGAA | |
| SCHEMBL998417 | 0.98 | DPP7 (0.50) | DPP7SLC6A3SLC6A2LMNAGAA | |
| SCHEMBL998415 | 0.98 | DPP7 (0.50) | DPP7SLC6A3SLC6A2LMNAGAA | |
| Hydrochloric Acid SCHEMBL2681538 | 0.96 | DPP7 (0.48) | DPP7SLC6A3SLC6A2LMNAGAA | |
| Hydrochloric Acid SCHEMBL2681539 | 0.96 | DPP7 (0.48) | DPP7SLC6A3SLC6A2LMNAGAA | |
| Hydrochloric Acid SCHEMBL10475896 | 0.96 | DPP7 (0.48) | DPP7SLC6A3SLC6A2LMNAGAA | |
| SCHEMBL10088097 | 0.91 | LMNA (0.38) | DPP7LMNAHSD17B10 | |
| SCHEMBL997678 | 0.81 | HSD17B10 (0.53) | LMNAHSD17B10 | |
| SCHEMBL18123012 | 0.81 | SLC6A2 (0.36) | DPP7SLC6A3SLC6A2LMNASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448931-B1 | Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine | GALDERMA RES & DEV (FR) | 2015-05-27 | — | — | EP | disclosed |
| EP-2448931-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | Galderma Research & Development (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001088-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |