Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | QDPR | P09417 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19219066 | 0.89 | MAPT (0.58) | MAPTLMNANOTUMCLK4ADRB2 | |
| SCHEMBL9974995 | 0.85 | RAB9A (0.52) | MAPTLMNAPIK3CANOTUMCLK4 | |
| SCHEMBL2712784 | 0.84 | MAPT (0.56) | MAPTLMNANOTUMCLK4ADRB2 | |
| SCHEMBL14655870 | 0.84 | MAPT (0.65) | MAPTLMNAPIK3CANOTUMQDPR | |
| SCHEMBL9974936 | 0.84 | MAPT (0.65) | MAPTLMNAPIK3CANOTUMQDPR | |
| SCHEMBL9974965 | 0.83 | NPC1 (0.48) | MAPTPIK3CACLK4ADRB2CYP2A6 | |
| SCHEMBL9974913 | 0.80 | NOTUM (0.71) | MAPTLMNAPIK3CANOTUMNPC1 | |
| SCHEMBL9974920 | 0.80 | NOTUM (0.71) | MAPTLMNAPIK3CANOTUMNPC1 | |
| SCHEMBL16625771 | 0.79 | CLK4 (0.61) | MAPTLMNACLK4ADRB2CYP2A6 | |
| SCHEMBL15389180 | 0.79 | MAPT (0.62) | MAPTLMNANOTUMQDPRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081541-A1 | 1, 2, 4, 5-SUBSTITUTED PHENYL DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |