Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GCGR | P47871 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9974936 | 0.88 | MAPT (0.65) | MAPTLMNAGCGRMAPK14SMN1; SMN2 | |
| SCHEMBL14655870 | 0.88 | MAPT (0.65) | MAPTLMNAGCGRMAPK14SMN1; SMN2 | |
| SCHEMBL94519 | 0.88 | MAPT (0.65) | MAPTLMNAGCGRMAPK14KDR | |
| SCHEMBL11988032 | 0.88 | MAPT (0.65) | MAPTLMNAGCGRMAPK14KDR | |
| SCHEMBL13019480 | 0.88 | MAPT (0.65) | MAPTLMNAGCGRMAPK14KDR | |
| SCHEMBL13728525 | 0.83 | MAPK14 (0.57) | MAPTLMNAGCGRMAPK14KDR | |
| SCHEMBL15389180 | 0.83 | MAPT (0.62) | MAPTLMNAGCGRMAPK14KDM4E | |
| SCHEMBL17006477 | 0.83 | ACHE (0.53) | MAPTLMNAKDM4EKMT2ANPC1 | |
| SCHEMBL3422005 | 0.82 | CYP46A1 (0.54) | MAPTLMNAGCGRMAPK14KDM4E | |
| SCHEMBL25871395 | 0.82 | CYP46A1 (0.54) | MAPTLMNAGCGRMAPK14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081541-A1 | 1, 2, 4, 5-SUBSTITUTED PHENYL DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |