SCHEMBL9974950

SCHEMBL9974950

c1ccc(-c2cccc(-c3cc(-c4cccc(-c5ccccc5)c4)c(-c4ccc(-c5cccnc5)cc4)cc3-c3ccc(-c4cccnc4)cc3)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 7/20 0.56
CYP11B1 P15538 6/20 0.56
CYP19A1 P11511 3/20 0.56
CYP17A1 P05093 1/20 0.56
CYP2A6 P11509 3/20 0.54
CYP1A2 P05177 2/20 0.54
ALDH1A1 P00352 1/20 0.54
CYP3A4 P08684 1/20 0.54
MKNK1 Q9BUB5 4/20 0.53
MKNK2 Q9HBH9 4/20 0.53
MEN1 O00255 1/20 0.53
PSIP1 O75475 1/20 0.53
AXL P30530 1/20 0.53
KMO O15229 1/20 0.51
PIK3CA P42336 1/20 0.48
KIF11 P52732 1/20 0.47
PGR P06401 1/20 0.47
TDP2 O95551 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9974947 0.93 CYP2A6 (0.62) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL9974924 0.93 CYP2A6 (0.62) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL14425488 0.91 CYP11B2 (0.66) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL14425482 0.91 CYP11B2 (0.66) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL27799996 0.89 CYP2A6 (0.58) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL31564925 0.89 CYP2A6 (0.58) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL11929803 0.89 CYP11B1 (0.49) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL13085392 0.89 CYP11B1 (0.49) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL18134278 0.89 CYP11B2 (0.63) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL17721072 0.89 CYP11B2 (0.63) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012081541-A1 1, 2, 4, 5-SUBSTITUTED PHENYL DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 (JP) 2012-06-21 WO disclosed