SCHEMBL997577

SCHEMBL997577

CCCOC(C)(O)OCCC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
HSD17B10 Q99714 1/20 0.31
ALDH1A1 P00352 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5013568 0.92
SCHEMBL26927354 0.89 TSHR (0.37) TSHRALDH1A1
SCHEMBL31195333 0.82 TSHR (0.40) TSHRALDH1A1
SCHEMBL29358441 0.81
SCHEMBL1262868 0.81
SCHEMBL28187812 0.79
SCHEMBL20145201 0.78 CES1 (0.45) TSHR
SCHEMBL26927358 0.78 HSD17B10 (0.37) TSHRHSD17B10
SCHEMBL5697594 0.78 HSD17B10 (0.32) HSD17B10ALDH1A1
SCHEMBL11289016 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3694938-B1 TIRE FOR VEHICLE WHEELS PIRELLI (IT) 2021-12-08 EP disclosed
EP-3694938-A1 TIRE FOR VEHICLE WHEELS Pirelli Tyre S.p.A. (IT) 2020-08-19 EP disclosed
WO-2019073378-A1 TIRE FOR VEHICLE WHEELS PIRELLI TYRE S.P.A. (IT) 2019-04-18 WO disclosed
EP-2264486-B1 Ophthalmic, tinted molding composition, molding having high Dk-value and method of its production NOVARTIS AG (CH) 2018-08-22 EP disclosed
US-9612455-B2 Extended wear ophthalmic lens NOVARTIS AG (CH) 2017-04-04 US disclosed
EP-1360527-B1 A TINTED, HIGH DK OPHTHALMIC MOLDING AND A METHOD FOR MAKING SAME NOVARTIS AG (CH) 2016-12-07 EP disclosed
US-20140022507-A1 Extended Wear Ophthalmic Lens CIBA VISION CORPORATION (US) 2014-01-23 US disclosed
US-8568626-B2 Extended wear ophthalmic lens CIBA VISION CORPORATION (US) 2013-10-29 US disclosed
US-8415404-B2 Extended wear ophthalmic lens CIBA VISION CORPORATION (US) 2013-04-09 US disclosed
EP-2270550-B1 Extended wear contact lens NOVARTIS AG (CH) 2012-08-22 EP disclosed
US-5849811-A Extended wear ophthalmic lens CIBA VISION CORPORATION (US) 1998-12-15 US disclosed
EP-0865615-A1 METHODS OF MANUFACTURING CONTACT LENSES Novartis AG (CH) 1998-09-23 EP disclosed
US-5789461-A BIOCOMPATIBLE LENS HAVING HIGH OXYGEN PERMEABILITY AND HIGH WATER PERMEABILITY CIBA VISION CORPORATION (US) 1998-08-04 US disclosed
US-5776999-A BALANCE OF OXYGEN AND WATER PERMEABILITY CIBA VISION CORPORATION (US) 1998-07-07 US disclosed
US-5760100-A OXYGEN AND ION OR WATER PERMEABILITY CIBA VISION CORPORATION (US) 1998-06-02 US disclosed
EP-0819258-A1 EXTENDED WEAR OPHTHALMIC LENS Novartis AG (CH) 1998-01-21 EP disclosed
EP-0809564-A1 METHOD OF DEBLOCKING, EXTRACTING AND CLEANING POLYMERIC ARTICLES WITH SUPERCRITICAL FLUID Novartis AG (CH) 1997-12-03 EP disclosed
WO-1997022019-A1 METHODS OF MANUFACTURING CONTACT LENSES NOVARTIS AG (CH) 1997-06-19 WO disclosed
WO-1996031792-A1 EXTENDED WEAR OPHTHALMIC LENS NOVARTIS AG (CH) 1996-10-10 WO disclosed
WO-1996026059-A1 METHOD OF DEBLOCKING, EXTRACTING AND CLEANING POLYMERIC ARTICLES WITH SUPERCRITICAL FLUID NOVARTIS AG (CH) 1996-08-29 WO disclosed