Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10383798 | 0.92 | PTPN2 (0.40) | DGAT2PTPN2PTPN1CNR1CHRM5 | |
| SCHEMBL9975801 | 0.89 | DGAT2 (0.40) | DGAT2PTPN2PTPN1CNR1CHRM5 | |
| SCHEMBL10365295 | 0.87 | DGAT2 (0.37) | DGAT2PTPN2PTPN1CNR1CHRM5 | |
| SCHEMBL9975780 | 0.85 | RAF1 (0.39) | CHRM5CHRM1LMNAL3MBTL1RAF1 | |
| SCHEMBL10381937 | 0.82 | PTPN2 (0.42) | DGAT2PTPN2PTPN1CNR1CHRM5 | |
| SCHEMBL9975803 | 0.81 | PTPN2 (0.41) | DGAT2PTPN2PTPN1CNR1CHRM5 | |
| SCHEMBL9975857 | 0.80 | PTPN2 (0.40) | DGAT2PTPN2PTPN1CNR1CHRM5 | |
| SCHEMBL9975687 | 0.80 | PTPN2 (0.40) | DGAT2PTPN2PTPN1CNR1CHRM5 | |
| SCHEMBL10382630 | 0.80 | RAF1 (0.41) | L3MBTL1RAF1 | |
| SCHEMBL10324265 | 0.79 | NR1I2 (0.39) | DGAT2PTPN2PTPN1CNR1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083105-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL DISCOVERY, INC. (US) | 2012-06-21 | — | — | WO | disclosed |