Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.76 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976499 | 0.92 | F10 (0.76) | F10RAB9AL3MBTL1 | |
| SCHEMBL9979748 | 0.91 | F10 (0.77) | F10 | |
| SCHEMBL9976455 | 0.86 | F10 (1.00) | F10RAB9ANPC1 | |
| SCHEMBL9976500 | 0.84 | F10 (0.81) | F10RAB9A | |
| SCHEMBL9976501 | 0.82 | F10 (0.68) | F10RAB9AL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL9976503 | 0.79 | F10 (0.70) | F10RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5399426 | 0.78 | F10 (1.00) | F10 | |
| SCHEMBL9928647 | 0.78 | F10 (0.84) | F10 | |
| SCHEMBL5409814 | 0.78 | F10 (0.84) | F10 | |
| SCHEMBL5406397 | 0.78 | F10 (0.83) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43481-E1 | Diazepan derivatives or salts thereof | ASTELLAS PHARMA INC. (JP) | 2012-06-19 | — | — | US | disclosed |