Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976499 | 0.90 | F10 (0.76) | F10RAB9AL3MBTL1 | |
| SCHEMBL9976493 | 0.87 | F10 (0.67) | F10RAB9AL3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL9976498 | 0.82 | F10 (0.76) | F10RAB9AL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL9976500 | 0.81 | F10 (0.81) | F10RAB9A | |
| SCHEMBL5404866 | 0.81 | F10 (1.00) | F10 | |
| Hydrochloric Acid SCHEMBL5428074 | 0.80 | F10 (1.00) | F10 | |
| SCHEMBL14350780 | 0.80 | RAB9A (0.58) | F10RAB9AL3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL9979748 | 0.80 | F10 (0.77) | F10 | |
| SCHEMBL5398111 | 0.79 | F10 (1.00) | F10RAB9A | |
| SCHEMBL14394521 | 0.78 | F10 (0.81) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43481-E1 | Diazepan derivatives or salts thereof | ASTELLAS PHARMA INC. (JP) | 2012-06-19 | — | — | US | disclosed |
| US-RE43481-E1 | Diazepan derivatives or salts thereof | ASTELLAS PHARMA INC. (JP) | 2012-06-19 | — | — | US | disclosed |
| US-7307074-B2 | Activated blood coagulation factor X inhibitor and also to such a pharmaceutical agent and particularly has an excellent activity by oral administration | ASTELLAS PHARMA INC. (JP) | 2007-12-11 | — | — | US | disclosed |
| US-7307074-B2 | Activated blood coagulation factor X inhibitor and also to such a pharmaceutical agent and particularly has an excellent activity by oral administration | ASTELLAS PHARMA INC. (JP) | 2007-12-11 | — | — | US | disclosed |