Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466994 | 0.84 | LMNA (0.47) | LMNAL3MBTL1TDP1ALDH1A1PDE4A | |
| SCHEMBL729097 | 0.75 | — | — | |
| SCHEMBL18201551 | 0.74 | LMNA (0.67) | LMNAL3MBTL1TDP1ALDH1A1PDE4A | |
| SCHEMBL22859930 | 0.72 | LMNA (0.73) | LMNAL3MBTL1TDP1ALDH1A1PDE4A | |
| SCHEMBL16522197 | 0.72 | TDP1 (0.47) | LMNAL3MBTL1TDP1ALDH1A1TSHR | |
| SCHEMBL1136599 | 0.72 | LMNA (0.37) | LMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL15044045 | 0.69 | LMNA (0.35) | LMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL17468046 | 0.69 | TDP1 (0.44) | LMNAL3MBTL1TDP1ALDH1A1TSHR | |
| SCHEMBL25278664 | 0.69 | — | — | |
| SCHEMBL9784825 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202430-B2 | Modified diamond particle surfaces and method | BRIGHAM YOUNG UNIVERSITY (US) | 2012-06-19 | — | — | US | disclosed |
| US-20100089832-A1 | MODIFIED DIAMOND PARTICLE SURFACES AND METHOD | BRIGHAM YOUNG UNIVERSITY | 2010-04-15 | — | — | US | disclosed |