Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976579 | 0.91 | KDM4E (0.41) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL14645360 | 0.86 | HSP90AB1 (0.37) | ACACAHSP90AB1ALDH1A1KDM4EGAA | |
| SCHEMBL14645283 | 0.84 | KDM4E (0.34) | ACACAHSP90AB1ALDH1A1KDM4EGAA | |
| SCHEMBL14773874 | 0.84 | ALDH1A1 (0.38) | ACACAHSP90AB1ALDH1A1KDM4EGAA | |
| SCHEMBL9976547 | 0.83 | AKR1B1 (0.33) | ALDH1A1RPS6KB2HTT | |
| SCHEMBL9976534 | 0.83 | HPGD (0.40) | ACACAALDH1A1KDM4EGAAGLA | |
| SCHEMBL15695240 | 0.82 | HSP90AB1 (0.34) | ACACAHSP90AB1ALDH1A1KDM4EGAA | |
| SCHEMBL15695231 | 0.81 | RXFP1 (0.33) | ACACAHSP90AB1ALDH1A1KDM4EGAA | |
| SCHEMBL14645436 | 0.81 | KDM4E (0.33) | ACACAHSP90AB1ALDH1A1KDM4EGAA | |
| SCHEMBL9976580 | 0.80 | KDM4E (0.47) | ALDH1A1KDM4EGAAGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350042-B1 | NOVEL THIOPHENE COMPOUNDS FOR USE IN THERAPHY | CPL BCX PHARMA AB (SE) | 2015-07-29 | — | — | EP | disclosed |
| US-8710246-B2 | Substituted thiophene pentamers | BIOCHROMIX NEWCO AB (SE) | 2014-04-29 | — | — | US | disclosed |
| US-8710246-B2 | Substituted thiophene pentamers | BIOCHROMIX NEWCO AB (SE) | 2014-04-29 | — | — | US | disclosed |
| US-20120157516-A1 | NOVEL THIOPHENE COMPOUNDS FOR USE IN THERAPY | BIOCHROMIX PHARMA AB | 2012-06-21 | — | — | US | disclosed |
| US-20120157516-A1 | NOVEL THIOPHENE COMPOUNDS FOR USE IN THERAPY | BIOCHROMIX PHARMA AB | 2012-06-21 | — | — | US | disclosed |
| WO-2010044743-A1 | NOVEL THIOPHENE COMPOUNDS FOR USE IN THERAPHY | BIOCHROMIX PHARMA AB (SE) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157516-A1 | NOVEL THIOPHENE COMPOUNDS FOR USE IN THERAPY | HSPE1, TTR, HTT | ACACA 2318/4885HSP90AB1 19/4885ALDH1A1 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.