Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560070 | 0.83 | HTT (0.55) | HCRTR1HTTTSHREPHX1HPGD | |
| SCHEMBL2665746 | 0.81 | TSHR (0.73) | HCRTR1HTTTSHRHPGDNAAA | |
| SCHEMBL8174236 | 0.79 | NAAA (0.67) | HCRTR1HTTTSHRHPGDNAAA | |
| SCHEMBL18381506 | 0.78 | HTT (0.44) | HCRTR1HTTTSHRHPGDNAAA | |
| SCHEMBL24696326 | 0.78 | TSHR (0.57) | HCRTR1HTTTSHRHPGDNAAA | |
| SCHEMBL18074482 | 0.78 | HTT (0.53) | HCRTR1HTTTSHRHPGDNAAA | |
| SCHEMBL12337626 | 0.78 | HPGD (0.56) | HCRTR1HTTTSHRHPGDKMT2A | |
| SCHEMBL10063838 | 0.78 | HCRTR1 (0.48) | HCRTR1HTTTSHRHPGDKMT2A | |
| SCHEMBL18381505 | 0.77 | OTC (0.45) | HTTTSHRHPGDKMT2AHSD17B10 | |
| SCHEMBL29798859 | 0.77 | NPC1 (0.58) | HTTTSHREPHX1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927720-B2 | Azabenzimidazoles as respiratory syncytial virus antiviral agents | JANSSEN R&D IRELAND (IE) | 2015-01-06 | — | — | US | disclosed |
| WO-2012080449-A1 | AZABENZIMIDAZOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2012-06-21 | — | — | WO | disclosed |