Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 10/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15908547 | 0.71 | TSHR (0.43) | TSHRMAPK1CNR2TP53POLB | |
| SCHEMBL15293766 | 0.71 | MAPK1 (0.43) | TSHRMAPK1CNR2TP53POLB | |
| Hydrochloric Acid SCHEMBL18275315 | 0.70 | TSHR (0.42) | TSHRMAPK1CNR2TP53POLB | |
| SCHEMBL9977913 | 0.70 | MAPK1 (0.42) | TSHRMAPK1CNR2POLBSMN1; SMN2 | |
| SCHEMBL9978053 | 0.68 | MAPK1 (0.39) | TSHRMAPK1CNR2POLBBCHE | |
| SCHEMBL9977957 | 0.66 | MAPK1 (0.49) | TSHRMAPK1CNR2TP53POLB | |
| SCHEMBL24306642 | 0.61 | — | — | |
| SCHEMBL24306147 | 0.61 | — | — | |
| SCHEMBL14733928 | 0.60 | TSHR (1.00) | TSHRMAPK1TP53POLBMAPT | |
| SCHEMBL7740380 | 0.59 | MAPK1 (0.76) | TSHRMAPK1TP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080449-A1 | AZABENZIMIDAZOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2012-06-21 | — | — | WO | disclosed |