⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24306642 | 0.76 | — | — | |
| SCHEMBL23767411 | 0.71 | LMNA (0.30) | — | |
| SCHEMBL24305933 | 0.70 | CNR2 (0.36) | — | |
| SCHEMBL23767660 | 0.67 | LMNA (0.36) | — | |
| SCHEMBL23767499 | 0.66 | CCNT1 (0.31) | — | |
| SCHEMBL24306195 | 0.66 | CCNT1 (0.33) | — | |
| SCHEMBL24306125 | 0.66 | CNR2 (0.36) | — | |
| SCHEMBL9977948 | 0.61 | TSHR (0.43) | — | |
| SCHEMBL18931172 | 0.57 | — | — | |
| SCHEMBL19896199 | 0.56 | KMT2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078380-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022078407-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-04-21 | — | — | WO | disclosed |