SCHEMBL9978151

SCHEMBL9978151

CCc1cc(-c2ccccc2)c(O)c(-c2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.51
PTPN2 P17706 1/20 0.51
PTPN6 P29350 1/20 0.51
BACE1 P56817 3/20 0.49
TP53 P04637 1/20 0.46
PDE4B Q07343 1/20 0.43
ESR2 Q92731 1/20 0.42
ALOX5 P09917 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HDAC4 P56524 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10454641 0.90 BACE1 (0.49) PTPN1PTPN2PTPN6BACE1TP53
SCHEMBL27685462 0.89 PTPN1 (0.46) PTPN1PTPN2PTPN6BACE1TP53
SCHEMBL8443634 0.87 PTPN1 (0.45) PTPN1PTPN2PTPN6BACE1TP53
SCHEMBL8641643 0.84 CNR1 (0.50) PTPN1PTPN2PTPN6BACE1PDE4B
SCHEMBL9620617 0.83 PTPN1 (0.70) PTPN1PTPN2PTPN6BACE1PDE4B
SCHEMBL200837 0.81 PSMB5 (0.52) PTPN1PTPN2PTPN6BACE1HPGD
SCHEMBL4286160 0.80 BACE1 (0.64) BACE1TP53ALOX5ALDH1A1HPGD
SCHEMBL9178161 0.79 PTPN1 (0.51) PTPN1PTPN2PTPN6BACE1PDE4B
SCHEMBL10931154 0.79 PTPN1 (0.51) PTPN1PTPN2PTPN6BACE1PDE4B
SCHEMBL27763835 0.79 TP53 (0.46) BACE1TP53PDE4BALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250341-B Catalyst system containing metallocene compound and method for catalyzing olefin polymerization by using catalyst system 北京引发科技有限公司 2020-12-11 CN disclosed
US-9314782-B2 Bis(trifluoromethanesulfonyl)ethyl-bearing compound and acid catalyst, and method for preparing same CENTRAL GLASS COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20140066659-A1 Bis(Trifluoromethanesulfonyl)Ethyl-Bearing Compound and Acid Catalyst, and Method for Preparing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-03-06 US disclosed
WO-2012081488-A1 BIS(TRIFLUOROMETHANESULFONYL)ETHYL-BEARING COMPOUND AND ACID CATALYST, AND METHOD FOR PREPARING SAME セントラル硝子株式会社 (JP) 2012-06-21 WO disclosed
CN-101593852-B Multibranched polymers and process for production thereof NIPPON SODA CO 2011-03-02 CN disclosed
CN-101593852-A Multibranched polymers and manufacture method thereof NIPPON SODA CO (JP) 2009-12-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140066659-A1 Bis(Trifluoromethanesulfonyl)Ethyl-Bearing Compound and Acid Catalyst, and Method for Preparing Same FOS, ETV6, ABL1 PTPN1 3640/4885PTPN2 3324/4885PTPN6 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.