Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978070 | 0.89 | CNR1 (0.48) | PPARDCNR2CNR1L3MBTL1NPC1 | |
| SCHEMBL9978203 | 0.89 | CNR1 (0.45) | PPARDCNR2CNR1ALDH1A1MAPT | |
| SCHEMBL9978177 | 0.88 | PPARD (0.52) | PPARDCNR2CNR1LMNAHTT | |
| SCHEMBL9978222 | 0.87 | CNR2 (0.50) | PPARDCNR2CNR1TRPV4L3MBTL1 | |
| SCHEMBL9978214 | 0.86 | CNR2 (0.48) | PPARDCNR2CNR1MAPTSMN1; SMN2 | |
| SCHEMBL9978202 | 0.85 | CNR1 (0.47) | PPARDCNR2CNR1 | |
| SCHEMBL9978218 | 0.85 | CNR1 (0.46) | PPARDCNR2CNR1L3MBTL1NPC1 | |
| SCHEMBL9978215 | 0.84 | CNR1 (0.48) | PPARDCNR2CNR1POLB | |
| SCHEMBL9978198 | 0.83 | PPARD (0.45) | PPARDCNR2CNR1LMNA | |
| SCHEMBL9978221 | 0.83 | CNR1 (0.45) | PPARDCNR2CNR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079164-A1 | ACTIVATORS OF CYLINDRICAL PROTEASES | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2012-06-21 | — | — | WO | disclosed |