Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978203 | 0.93 | CNR1 (0.45) | CNR1CNR2PPARDHSP90AA1CXCR5 | |
| SCHEMBL9978202 | 0.87 | CNR1 (0.47) | CNR1CNR2PPARD | |
| SCHEMBL9978070 | 0.85 | CNR1 (0.48) | CNR1CNR2PPARDNPC1RAB9A | |
| SCHEMBL9978198 | 0.85 | PPARD (0.45) | CNR1CNR2PPARDPDK1PDK2 | |
| SCHEMBL9978219 | 0.83 | PPARD (0.50) | CNR1CNR2PPARDMAPTNPC1 | |
| SCHEMBL9978218 | 0.81 | CNR1 (0.46) | CNR1CNR2PPARDNPC1RAB9A | |
| SCHEMBL9978222 | 0.81 | CNR2 (0.50) | CNR1CNR2PPARD | |
| SCHEMBL9978215 | 0.80 | CNR1 (0.48) | CNR1CNR2PPARD | |
| SCHEMBL9978177 | 0.80 | PPARD (0.52) | CNR1CNR2PPARDKMT2ASMN1; SMN2 | |
| SCHEMBL9978008 | 0.79 | CNR1 (0.48) | CNR1CNR2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079164-A1 | ACTIVATORS OF CYLINDRICAL PROTEASES | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2012-06-21 | — | — | WO | disclosed |