Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.59 |
| ▸ | FLT3 | P36888 | 3/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.59 |
| ▸ | KIT | P10721 | 2/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.59 |
| ▸ | RET | P07949 | 9/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1698832 | 0.90 | CSF1R (0.70) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9980605 | 0.86 | FLT3 (0.64) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9980487 | 0.84 | FLT3 (0.81) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9978910 | 0.83 | CSF1R (0.61) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9980459 | 0.81 | FLT3 (0.77) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL12068461 | 0.81 | CSF1R (0.56) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL12067861 | 0.80 | CSF1R (0.70) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9980593 | 0.80 | CSF1R (0.70) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9978582 | 0.79 | FLT3 (0.66) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL1698917 | 0.77 | CSF1R (0.66) | CSF1RFLT3PDGFRBKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011150201-A2 | AZOLYL AMIDE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2011-12-01 | — | — | WO | claimed |