Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 17/20 | 0.70 |
| ▸ | CSF1R | P07333 | 16/20 | 0.70 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.70 |
| ▸ | KIT | P10721 | 4/20 | 0.70 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.70 |
| ▸ | RET | P07949 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978708 | 0.94 | FLT3 (0.75) | FLT3CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL9978705 | 0.92 | FLT3 (0.83) | FLT3CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL12067855 | 0.92 | FLT3 (0.64) | FLT3CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL1698608 | 0.90 | FLT3 (0.85) | FLT3CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL9978727 | 0.90 | FLT3 (0.61) | FLT3CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL9978567 | 0.90 | FLT3 (0.69) | FLT3CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL9978679 | 0.90 | FLT3 (0.78) | FLT3CSF1RPDGFRBKITPDGFRA | |
| Hydrochloric Acid SCHEMBL9978897 | 0.89 | FLT3 (0.68) | FLT3CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL9978760 | 0.88 | FLT3 (0.83) | FLT3CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL9978703 | 0.87 | FLT3 (0.65) | FLT3CSF1RPDGFRBKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011150201-A2 | AZOLYL AMIDE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2011-12-01 | — | — | WO | claimed |
| WO-2011150201-A2 | AZOLYL AMIDE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2011-12-01 | — | — | WO | disclosed |