SCHEMBL9978633

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24101491	0.88	KDM4E (0.52)	MCL1KDM4EALDH1A1HPGDNPSR1
	SCHEMBL12065186	0.87	KDM4E (0.55)	MCL1KDM4EALDH1A1HPGDNPSR1
	SCHEMBL9978740	0.86	MCL1 (0.60)	MCL1KDM4EALDH1A1HPGDNPSR1
	SCHEMBL3741758	0.80	KDM4E (0.60)	KDM4EALDH1A1HPGDNPSR1L3MBTL1
	SCHEMBL8967057	0.79	KDM4E (0.56)	KDM4EALDH1A1HPGDNPSR1L3MBTL1
	SCHEMBL30855494	0.79	MCL1 (0.72)	MCL1KDM4EALDH1A1ERN1CYP1A2
	SCHEMBL18517642	0.79	MCL1 (0.72)	MCL1KDM4EALDH1A1ERN1CYP1A2
	SCHEMBL8966782	0.78	KDM4E (0.59)	KDM4EALDH1A1HPGDNPSR1L3MBTL1
	SCHEMBL2131809	0.78	KDM4E (0.59)	KDM4EALDH1A1HPGDNPSR1
	SCHEMBL870174	0.78	BRD4 (0.47)	MCL1KDM4EALDH1A1HPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.