Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897604 | 0.90 | PIM1 (0.53) | BRD4PIM1PIM3NR4A2CREBBP | |
| SCHEMBL70381 | 0.85 | BRD4 (0.59) | BRD4NR4A2CREBBPLMNATSHR | |
| SCHEMBL29434198 | 0.85 | BRD4 (0.59) | BRD4NR4A2CREBBPLMNATSHR | |
| SCHEMBL30717654 | 0.85 | BRD4 (0.46) | BRD4NR4A2CREBBPLMNATSHR | |
| SCHEMBL883625 | 0.85 | BRD4 (0.46) | BRD4NR4A2CREBBPLMNATSHR | |
| SCHEMBL1665898 | 0.82 | ALDH1A1 (0.47) | LMNAKDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL1036677 | 0.82 | HPGD (0.46) | BRD4NR4A2CREBBPLMNATSHR | |
| SCHEMBL1036678 | 0.82 | HPGD (0.46) | BRD4NR4A2CREBBPLMNATSHR | |
| SCHEMBL870987 | 0.81 | CYP1A2 (0.49) | BRD4NR4A2CREBBPLMNAKDM4E | |
| SCHEMBL870986 | 0.81 | CYP1A2 (0.49) | BRD4NR4A2CREBBPLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490406-A | Preparation method of 4-formylnaphthalene-1-carboxylic acid methyl ester | 长沙创新药物工业技术研究院有限公司 | 2025-02-21 | — | — | CN | claimed |
| CN-117886695-A | Synthesis method of aforana key intermediate 4-formyl-1-methyl naphthoate | 浙江工业大学 | 2024-04-16 | — | — | CN | claimed |
| CN-117776883-A | Preparation method of aromatic ketone compound containing diaryl methane structure | 湖南科技大学 | 2024-03-29 | — | — | CN | claimed |
| US-20260070879-A1 | ISOXAZOLINE DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2026-03-12 | — | — | US | disclosed |
| US-12497370-B2 | Isoxazoline derivatives | ELANCO TIERGESUNDHEIT AG (CH) | 2025-12-16 | — | — | US | disclosed |
| CN-120004816-A | Isoxazoline derivatives | 礼蓝动物保健有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-115210221-B | Isoxazoline derivatives as pesticides | 礼蓝动物保健有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119490406-A | Preparation method of 4-formylnaphthalene-1-carboxylic acid methyl ester | 长沙创新药物工业技术研究院有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-119490406-A | Preparation method of 4-formylnaphthalene-1-carboxylic acid methyl ester | 长沙创新药物工业技术研究院有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-119490406-A | Preparation method of 4-formylnaphthalene-1-carboxylic acid methyl ester | 长沙创新药物工业技术研究院有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-117886695-A | Synthesis method of aforana key intermediate 4-formyl-1-methyl naphthoate | 浙江工业大学 | 2024-04-16 | — | — | CN | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |
| US-4016195-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
| US-4000275-A | BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3957846-A | OPTICAL BRIGHTENERS, LACQUERS, SYNTHETIC FIBERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | BRD4 461/4885PIM1 3393/4885PIM3 3949/4885 |
| US-12497370-B2 | Isoxazoline derivatives | CYP3A7, CYP4X1, CYP2A7 | BRD4 1245/4885PIM1 3109/4885PIM3 3019/4885 |
| US-20260070879-A1 | ISOXAZOLINE DERIVATIVES | CHRM1, CBR3, AFF1 | BRD4 788/4885PIM1 3607/4885PIM3 2790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.