Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979129 | 0.83 | PPARG (0.32) | — | |
| SCHEMBL9979018 | 0.80 | OPRL1 (0.35) | CYP2C9OPRL1ALDH1A1LMNAMAPT | |
| SCHEMBL15834706 | 0.78 | OPRL1 (0.40) | CYP2C9OPRL1ALDH1A1LMNAMAPT | |
| SCHEMBL21609926 | 0.78 | OPRL1 (0.40) | CYP2C9OPRL1ALDH1A1LMNAMAPT | |
| SCHEMBL9979185 | 0.78 | CYP2C9 (0.33) | CYP2C9OPRL1ALDH1A1LMNAMAPT | |
| SCHEMBL17528172 | 0.77 | HTR2C (0.43) | — | |
| SCHEMBL17068419 | 0.77 | SLC6A2 (0.36) | — | |
| SCHEMBL12836498 | 0.76 | CYP2C9 (0.35) | CYP2C9OPRL1ALDH1A1LMNAMAPT | |
| SCHEMBL9898765 | 0.75 | S1PR1 (0.32) | — | |
| SCHEMBL12024320 | 0.75 | GAA (0.34) | CYP2C9OPRL1MAPTMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389073-B2 | Four-ring liquid crystal compound having tetrahydropyran and 2,2′,3,3′-tetrafluorobiphenyl, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-05 | — | — | US | disclosed |
| US-8389073-B2 | Four-ring liquid crystal compound having tetrahydropyran and 2,2′,3,3′-tetrafluorobiphenyl, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-05 | — | — | US | disclosed |
| US-8389073-B2 | Four-ring liquid crystal compound having tetrahydropyran and 2,2′,3,3′-tetrafluorobiphenyl, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-05 | — | — | US | disclosed |
| US-20110297881-A1 | FOUR-RING LIQUID CRYSTAL COMPOUND HAVING TETRAHYDROPYRAN AND 2,2',3,3'-TETRAFLUOROBIPHENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO PETROCHEMICAL CORPORATION (JP) | 2011-12-08 | — | — | US | disclosed |
| US-20110297881-A1 | FOUR-RING LIQUID CRYSTAL COMPOUND HAVING TETRAHYDROPYRAN AND 2,2',3,3'-TETRAFLUOROBIPHENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO PETROCHEMICAL CORPORATION (JP) | 2011-12-08 | — | — | US | disclosed |
| US-20110297881-A1 | FOUR-RING LIQUID CRYSTAL COMPOUND HAVING TETRAHYDROPYRAN AND 2,2',3,3'-TETRAFLUOROBIPHENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO PETROCHEMICAL CORPORATION (JP) | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110297881-A1 | FOUR-RING LIQUID CRYSTAL COMPOUND HAVING TETRAHYDROPYRAN AND 2,2',3,3'-TETRAFLUOROBIPHENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CCT4, TEC, TCF4 | CYP2C9 343/4885OPRL1 2738/4885ALDH1A1 2555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.