SCHEMBL9978995

SCHEMBL9978995

O=C(CC(CC(=O)Nc1cc(F)cc(F)c1)C(=O)Nc1cc(F)cc(F)c1)Nc1cc(F)cc(F)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
SLC6A9 P48067 3/20 0.40
KDM4E B2RXH2 1/20 0.39
TSHR P16473 1/20 0.39
LMNA P02545 2/20 0.38
TACR1 P25103 1/20 0.38
ALDH1A1 P00352 1/20 0.38
SLC6A5 Q9Y345 1/20 0.38
EGFR P00533 1/20 0.37
P2RX1 P51575 1/20 0.36
P2RX4 Q99571 1/20 0.36
P2RX7 Q99572 1/20 0.36
GAA P10253 1/20 0.36
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9978869 0.82 GAA (0.56) MEN1KMT2AHTTNPSR1KDM4E
SCHEMBL13018942 0.80 HTT (0.66) MEN1KMT2AHTTNPSR1TSHR
SCHEMBL9979140 0.79 HTT (0.69) MEN1KMT2AHTTNPSR1KDM4E
SCHEMBL9979240 0.78 TACR1 (0.62) LMNATACR1ALDH1A1P2RX1P2RX7
SCHEMBL16417973 0.76 HTT (0.56) MEN1KMT2AHTTNPSR1LMNA
SCHEMBL3843342 0.76 GAA (0.44) MEN1KMT2AHTTNPSR1SLC6A9
SCHEMBL16417972 0.73 TSHR (0.39) MEN1KMT2AHTTNPSR1SLC6A9
SCHEMBL13019006 0.73 KMT2A (0.56) MEN1KMT2ATSHRALDH1A1GAA
SCHEMBL2713283 0.73 KMT2A (0.56) MEN1KMT2AHTTNPSR1SLC6A9
SCHEMBL243556 0.73 MEN1 (0.48) MEN1KMT2ASLC6A9ALDH1A1SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed