SCHEMBL9979240

SCHEMBL9979240

O=C(CC(CC(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 2/20 0.62
ALDH1A1 P00352 2/20 0.62
LMNA P02545 1/20 0.58
ACP1 P24666 3/20 0.56
MAPT P10636 1/20 0.50
PTPN7 P35236 1/20 0.48
PTPN12 Q05209 1/20 0.48
PTPN13 Q12923 1/20 0.48
SSU72 Q9NP77 1/20 0.48
GPR35 Q9HC97 1/20 0.47
P2RX1 P51575 4/20 0.46
THRB P10828 1/20 0.46
RHOC P08134 1/20 0.44
RHOA P61586 1/20 0.44
P2RX7 Q99572 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9978854 0.87 TACR1 (0.67) TACR1ALDH1A1LMNAACP1MAPT
SCHEMBL9978995 0.78 MEN1 (0.43) TACR1ALDH1A1LMNAMAPTP2RX1
SCHEMBL263685 0.76 LMNA (0.65) TACR1ALDH1A1LMNAACP1MAPT
SCHEMBL14521754 0.76 MAPT (0.61) TACR1ALDH1A1LMNAACP1MAPT
SCHEMBL11306123 0.76 MAPT (0.61) TACR1ALDH1A1LMNAACP1MAPT
SCHEMBL10750113 0.76 LMNA (0.65) TACR1ALDH1A1LMNAACP1MAPT
SCHEMBL14263848 0.76 ALDH1A1 (0.65) TACR1ALDH1A1LMNAACP1MAPT
Hydrochloric Acid SCHEMBL3277457 0.75 LMNA (0.63) TACR1ALDH1A1LMNAACP1MAPT
SCHEMBL9979140 0.75 HTT (0.69) LMNAMAPTTHRB
SCHEMBL13989327 0.74 HSD17B10 (0.55) TACR1ALDH1A1LMNAACP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed