SCHEMBL9979035

SCHEMBL9979035

CC(C)c1ccccc1NC(=O)c1cc(C(=O)Nc2ccccc2C(C)C)cc(C(=O)Nc2ccccc2C(C)C)c1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.60
LMNA P02545 4/20 0.56
KMT2A Q03164 2/20 0.56
RECQL P46063 1/20 0.54
MEN1 O00255 1/20 0.53
TOP1 P11387 1/20 0.51
TOP2A P11388 1/20 0.51
TOP2B Q02880 1/20 0.51
GAA P10253 2/20 0.51
HTT P42858 1/20 0.51
KCNK3 O14649 1/20 0.51
KCNK9 Q9NPC2 1/20 0.51
CFTR P13569 1/20 0.51
ALDH1A1 P00352 1/20 0.51
LPAR1 Q92633 2/20 0.50
AKR1C3 P42330 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15614451 0.89 LMNA (0.70) MAPTLMNAKMT2AMEN1GAA
SCHEMBL23309633 0.86 RECQL (0.52) MAPTLMNAKMT2ARECQLMEN1
SCHEMBL21311177 0.85 RXFP1 (0.55) MAPTRECQLGAAALDH1A1
SCHEMBL8461958 0.85 LMNA (0.59) MAPTLMNAKMT2AMEN1GAA
SCHEMBL10765573 0.83 MAPT (0.55) MAPTLMNAKMT2AMEN1GAA
SCHEMBL21311176 0.81 PTGS1 (0.62) MAPTLMNAKMT2AGAAALDH1A1
SCHEMBL12674224 0.81 HPGD (0.56) MAPTLMNAKMT2AGAAKCNK3
SCHEMBL2341773 0.81 MAPT (0.58) MAPTKMT2ARECQLCFTRLPAR1
SCHEMBL1520489 0.79 GRIN2D (0.60) MAPTKMT2ARECQLLPAR1
SCHEMBL757161 0.79 MAPT (0.57) MAPTKMT2ARECQLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed