Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | LATS1 | O95835 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12058167 | 0.94 | GBA1 (0.41) | GBA1USP30IRAK4DGAT2MAPT | |
| SCHEMBL9979238 | 0.69 | LATS1 (0.61) | ALDH1A1LATS1USP2LMNATSHR | |
| SCHEMBL1623929 | 0.69 | SMAD3 (0.53) | MAPTALDH1A1PPARDPPARANPSR1 | |
| SCHEMBL1623761 | 0.69 | SMAD3 (0.53) | MAPTALDH1A1PPARDPPARANPSR1 | |
| SCHEMBL1623765 | 0.69 | SMAD3 (0.53) | MAPTALDH1A1PPARDPPARANPSR1 | |
| SCHEMBL12039897 | 0.68 | CYP1A2 (0.55) | GBA1MAPTALDH1A1GAALATS1 | |
| SCHEMBL9979316 | 0.66 | CYP1A2 (0.54) | GBA1MAPTALDH1A1GAALATS1 | |
| SCHEMBL28770960 | 0.65 | SMAD3 (0.48) | MAPTALDH1A1NPSR1LMNATSHR | |
| SCHEMBL31333706 | 0.65 | ADORA1 (0.41) | IRAK4MAPK1 | |
| SCHEMBL27713969 | 0.65 | SMAD3 (0.48) | MAPTALDH1A1NPSR1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319409-A1 | 7-AZA-QUINAZOLINE PDE10 INHIBITORS | COX CHRISTOPHER D (US) | 2011-12-29 | — | — | US | claimed |
| US-20110319409-A1 | 7-AZA-QUINAZOLINE PDE10 INHIBITORS | COX CHRISTOPHER D (US) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319409-A1 | 7-AZA-QUINAZOLINE PDE10 INHIBITORS | PDE5A, PDE12, PDE7B | GBA1 355/4885USP30 575/4885IRAK4 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.