Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979212 | 0.91 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL9979292 | 0.88 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL9979328 | 0.87 | HDAC3 (0.54) | NPC1RAB9ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL9979214 | 0.82 | NLRP3 (0.51) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9312694 | 0.81 | POLB (0.67) | NPC1RAB9ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL14349974 | 0.80 | SPHK1 (0.56) | NPC1RAB9ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL9979332 | 0.80 | POLB (0.63) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10117151 | 0.80 | POLB (0.60) | NPC1RAB9ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL9979344 | 0.79 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2POLBHPGD | |
| SCHEMBL6123671 | 0.79 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492468-B2 | Polypropylene resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-23 | — | — | US | disclosed |
| US-20110301268-A1 | POLYPROPYLENE RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-08 | — | — | US | disclosed |