Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460753 | 0.98 | TLR4 (0.38) | TLR4 | |
| SCHEMBL30846912 | 0.98 | TLR4 (0.38) | TLR4 | |
| SCHEMBL6460758 | 0.98 | TLR4 (0.38) | TLR4 | |
| SCHEMBL6458146 | 0.93 | TLR4 (0.35) | TLR4 | |
| SCHEMBL6453271 | 0.93 | TLR4 (0.35) | TLR4 | |
| SCHEMBL6453263 | 0.93 | TLR4 (0.35) | TLR4 | |
| SCHEMBL10837428 | 0.93 | TLR4 (0.35) | TLR4 | |
| SCHEMBL6464689 | 0.91 | TLR4 (0.35) | TLR4 | |
| SCHEMBL6464686 | 0.91 | TLR4 (0.35) | TLR4 | |
| SCHEMBL2885681 | 0.90 | TLR4 (0.38) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999197-B2 | Compound having a five-membered ring, the liquid crystal composition and the liquid crystal display device | JNC CORPORATION (JP) | 2015-04-07 | — | — | US | disclosed |
| US-20140054499-A1 | COMPOUND HAVING A FIVE-MEMBERED RING, THE LIQUID CRYSTAL COMPOSITION AND THE LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2014-02-27 | — | — | US | disclosed |
| US-20110309300-A1 | COMPOUND HAVING A FIVE-MEMBERED RING, THE LIQUID CRYSTAL COMPOSITION AND THE LIQUID CRYSTAL DISPLAY DEVICE | CHISSO PETROCHEMICAL CORPORATION (JP) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110309300-A1 | COMPOUND HAVING A FIVE-MEMBERED RING, THE LIQUID CRYSTAL COMPOSITION AND THE LIQUID CRYSTAL DISPLAY DEVICE | CTNND1, HCN1, CTNNA1 | TLR4 3605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.