Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 9/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491301 | 0.87 | AVPR2 (0.53) | AVPR2AVPR1AMAPTTP53LMNA | |
| SCHEMBL4505459 | 0.86 | AVPR2 (0.51) | AVPR2AVPR1AMAPTTP53LMNA | |
| SCHEMBL6127314 | 0.86 | AVPR2 (0.51) | AVPR2AVPR1AMAPTTP53LMNA | |
| SCHEMBL8237640 | 0.83 | AVPR2 (0.49) | AVPR2AVPR1AMAPTTP53LMNA | |
| SCHEMBL8232549 | 0.83 | AVPR2 (0.49) | AVPR2AVPR1AMAPTTP53LMNA | |
| SCHEMBL8233213 | 0.83 | AVPR2 (0.60) | AVPR2AVPR1AMAPTTP53 | |
| SCHEMBL9978877 | 0.83 | AVPR2 (0.50) | AVPR2AVPR1AMAPTTP53LMNA | |
| SCHEMBL4489066 | 0.83 | AVPR2 (0.52) | AVPR2AVPR1AMAPTTP53LMNA | |
| SCHEMBL3986255 | 0.83 | AVPR2 (0.58) | AVPR2AVPR1AMAPTTP53 | |
| SCHEMBL3979687 | 0.82 | AVPR2 (0.60) | AVPR2AVPR1AMAPTTP53P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084481-B2 | Substituted arylimidazolone and triazolone as inhibitors of vasopressin receptors | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-12-27 | — | — | US | disclosed |