Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578213 | 0.93 | HTT (0.40) | HTTKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL13215927 | 0.92 | HTT (0.40) | HTTKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL9979699 | 0.91 | GAA (0.40) | HTTKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL14578184 | 0.90 | KMT2A (0.44) | HTTKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL5341760 | 0.90 | HTT (0.43) | HTTKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL9979544 | 0.90 | HTT (0.43) | HTTKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL13215908 | 0.89 | KDM4E (0.39) | HTTKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL9979577 | 0.88 | HTT (0.41) | HTTKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL14578299 | 0.87 | HTT (0.45) | HTTKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL14578061 | 0.85 | KDM4E (0.41) | HTTKDM4ETDP1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |