Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 5/20 | 0.43 |
| ▸ | CBLB | Q13191 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 4/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979597 | 0.85 | UGCG (0.43) | UGCGNPC1RAB9APKMTHRB | |
| SCHEMBL9979474 | 0.84 | UGCG (0.41) | UGCGCBLBNPC1RAB9APKM | |
| SCHEMBL9979553 | 0.83 | UGCG (0.43) | UGCGCBLBNPC1RAB9APKM | |
| SCHEMBL9979552 | 0.81 | UGCG (0.41) | UGCGCBLBNPC1RAB9APKM | |
| SCHEMBL9979596 | 0.81 | KDM4E (0.47) | UGCGNPC1RAB9APKMTHRB | |
| SCHEMBL9979466 | 0.80 | UGCG (0.44) | UGCGNPC1RAB9APKMTHRB | |
| SCHEMBL28623206 | 0.79 | NPC1 (0.68) | NPC1RAB9APKMTHRBTP53 | |
| SCHEMBL9979662 | 0.78 | NPC1 (0.59) | UGCGCBLBNPC1RAB9APKM | |
| SCHEMBL10086535 | 0.75 | CBLB (0.52) | UGCGCBLBNPC1RAB9APKM | |
| SCHEMBL4419914 | 0.74 | CCR9 (0.47) | TRPM8MAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |