SCHEMBL9979474 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	UGCG	Q16739	4/20	0.41

▸	NPC1	O15118	2/20	0.40

▸	RAB9A	P51151	2/20	0.40

▸	PKM	P14618	1/20	0.40

▸	TP53	P04637	1/20	0.38

▸	MAPT	P10636	1/20	0.38

▸	SMN1; SMN2	Q16637	1/20	0.38

▸	THRB	P10828	1/20	0.37

▸	CBLB	Q13191	7/20	0.37

▸	LIPE	Q05469	5/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9979552	0.88	UGCG (0.41)	UGCGNPC1RAB9APKMTP53
SCHEMBL9979659	0.84	UGCG (0.43)	UGCGNPC1RAB9APKMTP53
SCHEMBL9979554	0.84	UGCG (0.43)	UGCGCBLB
SCHEMBL9979597	0.81	UGCG (0.43)	UGCGNPC1RAB9APKMTP53
SCHEMBL9979484	0.81	UGCG (0.43)	UGCGNPC1RAB9APKMTP53
SCHEMBL9979600	0.80	UGCG (0.42)	UGCGNPC1RAB9APKMTP53
SCHEMBL9979599	0.80	NPC1 (0.55)	UGCGNPC1RAB9APKMTP53
SCHEMBL9979596	0.79	KDM4E (0.47)	UGCGNPC1RAB9APKMTHRB
SCHEMBL9979466	0.77	UGCG (0.44)	UGCGNPC1RAB9APKMTP53
SCHEMBL28623206	0.76	NPC1 (0.68)	NPC1RAB9APKMTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012081570-A1	LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR	あすか製薬株式会社 (JP)	2012-06-21	—	—	WO	disclosed