Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6108015 | 0.90 | PTGDR2 (0.61) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL2561249 | 0.86 | PTGDR2 (0.65) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL8389278 | 0.86 | PTGDR2 (0.65) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL2560503 | 0.86 | PTGDR2 (0.65) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL2187687 | 0.83 | PTGDR2 (0.66) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL354835 | 0.81 | PTGDR2 (1.00) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL9695894 | 0.80 | PTGDR2 (0.72) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL1752352 | 0.80 | PTGDR2 (0.72) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL31428467 | 0.80 | PTGDR2 (0.72) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL1287954 | 0.80 | PTGDR2 (0.72) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716153-B1 | METHODS, COMPOSITIONS, AND APPARATUSES FOR FORMING MACROCYCLIC COMPOUNDS | JOHNSON THOMAS E (US) | 2013-10-09 | — | — | EP | disclosed |
| US-20120157658-A1 | METHODS, COMPOSITIONS, AND APPARATUSES FOR FORMING MACROCYCLIC COMPOUNDS | JOHNSON THOMAS E (US) | 2012-06-21 | — | — | US | disclosed |
| US-8053571-B2 | Methods, compositions, and apparatuses for forming macrocyclic compounds | JOHNSON THOMAS E | 2011-11-08 | — | — | US | disclosed |
| US-20100216970-A1 | METHODS, COMPOSITIONS, AND APPARATUSES FOR FORMING MACROCYCLIC COMPOUNDS | JOHNSON THOMAS E | 2010-08-26 | — | — | US | disclosed |
| US-7709632-B2 | such as porphyrins, chlorins, texaphyrins via cyclization, oligomerization | JOHNSON THOMAS E | 2010-05-04 | — | — | US | disclosed |
| US-20070217965-A1 | Methods, compositions, and apparatuses for forming macrocyclic compounds | JOHNSON THOMAS E | 2007-09-20 | — | — | US | disclosed |