SCHEMBL354835

SCHEMBL354835

O=Cc1ccccc1OCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 2/20 1.00
ALDH1A1 P00352 4/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
HPGD P15428 2/20 0.66
HTT P42858 1/20 0.66
POLB P06746 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
GLA P06280 1/20 0.58
TDP1 Q9NUW8 2/20 0.54
KDM4E B2RXH2 2/20 0.54
MMP2 P08253 1/20 0.54
MMP3 P08254 1/20 0.54
MMP13 P45452 1/20 0.54
MMP14 P50281 1/20 0.54
KMT2A Q03164 5/20 0.52
MEN1 O00255 4/20 0.52
ALOX15 P16050 1/20 0.52
GAA P10253 2/20 0.52
LMNA P02545 1/20 0.52
NPC1 O15118 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1382747 0.84 PTGDR2 (0.73) PTGDR2ALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL1752352 0.84 PTGDR2 (0.72) PTGDR2ALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL2557964 0.84 PTGDR2 (0.72) PTGDR2ALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL9695894 0.84 PTGDR2 (0.72) PTGDR2ALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL6687183 0.84 PTGDR2 (0.72) PTGDR2ALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL31428467 0.84 PTGDR2 (0.72) PTGDR2ALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL1287954 0.84 PTGDR2 (0.72) PTGDR2ALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL4350483 0.83 PTGDR2 (0.71) PTGDR2ALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL5304037 0.82 PTGDR2 (0.70) PTGDR2ALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL10051821 0.82 PTGDR2 (0.68) PTGDR2ALDH1A1SMN1; SMN2HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613362-A Preparation method of 3-amino-2, 3-dihydrobenzofuran compound 江西师范大学 2025-03-14 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
WO-2020032813-A1 NEW 5-SUBSTITUTED DERIVATIVES OF 5-HYDRAZINO-3-METHYLISOTHIAZOLE-4- ACID CARBOXYLIC ACID WITH ANTI-TUMOR ACTIVITY AND THE METHOD OF THEIR PREPARATION AND USES UNIWERSYTET MEDYCZNY IM. PIASTÓW ŚLĄSKICH WE WROCŁAWIU (PL) 2020-02-13 WO claimed
CN-105037269-B Substituted pyrazolecarboxylic ketone secretory protease inhibitors and preparation method thereof 中国人民解放军第二军医大学 2018-01-19 CN claimed
WO-2013175499-A2 POLYMORPHIC FORM OF 5-(4-[4-(5-CYANO-1H-INDOL-3- YL)BUTYL]PIPERAZIN-1-YL) BENZOFURAN-2-CARBOXAMIDE CADILA HEALTHCARE LIMITED (IN) 2013-11-28 WO claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 US claimed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
EP-1215210-B1 Benzofurans MERCK PATENT GMBH (DE) 2006-10-18 EP claimed
EP-0738722-A1 5-Amino-benzofuran-2-carboxylic acid derivatives MERCK PATENT GmbH (DE) 1996-10-23 EP claimed
EP-0630888-A1 IMIDAZOLINE DERIVATIVE, PRODUCTION THEREOF, AND BLOOD PRESSURE RETENTIVE Maeda, Hiroshi (JP) 1994-12-28 EP claimed
US-4654435-A WITH ORGANIC COMPOUNDS HAVING BOTH A CARBOXYL GROUP AND AN ALDEHYDE GROUP NIPPON ZEON CO., LTD. (JP) 1987-03-31 US claimed
EP-0087109-B1 MODIFIED RUBBER COMPOSITION NIPPON ZEON CO., LTD. (JP) 1986-10-29 EP claimed
EP-0087110-B1 PROCESS FOR MODIFYING RUBBERS NIPPON ZEON CO., LTD. (JP) 1986-10-29 EP claimed
US-4412031-A CARBON BLACK NIPPON ZEON CO., LTD. (JP) 1983-10-25 US claimed
US-4412041-A IN PRESENCE OF ACID CATALYSTS NIPPON ZEON CO. LTD. (JP) 1983-10-25 US claimed
EP-0087109-A1 Modified rubber composition NIPPON ZEON CO., LTD. (JP) 1983-08-31 EP claimed
EP-0087110-A1 Process for modifying rubbers NIPPON ZEON CO., LTD. (JP) 1983-08-31 EP claimed
US-4017313-A Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 PTGDR2 2441/4885ALDH1A1 83/4885SMN1; SMN2 3654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.