Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979542 | 0.89 | LMNA (0.50) | LMNAPOLBGAANTRK1CHRM3 | |
| SCHEMBL9979682 | 0.78 | LMNA (0.49) | LMNAPOLBGAANTRK1MAPK1 | |
| SCHEMBL9979686 | 0.76 | LMNA (0.36) | LMNAPOLBGAAMAPK1CHRM3 | |
| SCHEMBL13215978 | 0.76 | LMNA (0.43) | LMNAPOLBGAANTRK1MAPK1 | |
| SCHEMBL1085471 | 0.76 | LMNA (0.57) | LMNAPOLBNTRK1TACR1IRAK4 | |
| SCHEMBL14578389 | 0.75 | LMNA (0.47) | LMNAPOLBGAANTRK1CHRM3 | |
| SCHEMBL9979547 | 0.75 | LMNA (0.47) | LMNAPOLBGAANTRK1CHRM3 | |
| SCHEMBL4100026 | 0.75 | NTRK1 (0.56) | LMNAPOLBNTRK1CHRM3TACR1 | |
| SCHEMBL13936348 | 0.75 | NTRK1 (0.59) | LMNAPOLBNTRK1MAPK1CHRM3 | |
| SCHEMBL14266795 | 0.75 | LMNA (0.54) | LMNAPOLBGAANTRK1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |