Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 13/20 | 0.56 |
| ▸ | PPARA | Q07869 | 11/20 | 0.56 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | UGCG | Q16739 | 4/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979615 | 0.92 | PPARD (0.46) | PPARDPPARAPPARGMRGPRX4UGCG | |
| SCHEMBL9979535 | 0.92 | PPARD (0.67) | PPARDPPARAPPARG | |
| SCHEMBL9979576 | 0.91 | PPARD (0.42) | PPARDPPARAPPARGUGCGITGB3 | |
| SCHEMBL9979532 | 0.84 | PPARD (0.55) | PPARDPPARAPPARGMRGPRX4UGCG | |
| SCHEMBL9979500 | 0.83 | PPARD (0.51) | PPARDPPARAPPARGUGCGITGB3 | |
| SCHEMBL9979607 | 0.80 | FFAR1 (0.39) | PPARDPPARAPPARGMRGPRX4UGCG | |
| SCHEMBL9979628 | 0.79 | FFAR1 (0.46) | PPARDPPARG | |
| SCHEMBL9979530 | 0.79 | FFAR1 (0.46) | PPARDPPARG | |
| SCHEMBL9979510 | 0.78 | PPARD (0.53) | PPARDPPARAPPARG | |
| SCHEMBL5639274 | 0.77 | PPARA (0.81) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |