Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | UGCG | Q16739 | 3/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979500 | 0.93 | PPARD (0.51) | PPARDPPARAPPARGUGCGITGB3 | |
| SCHEMBL9979692 | 0.91 | PPARD (0.56) | PPARDPPARAPPARGUGCGITGB3 | |
| SCHEMBL9979615 | 0.91 | PPARD (0.46) | PPARDPPARAPPARGUGCGITGB3 | |
| SCHEMBL9979535 | 0.82 | PPARD (0.67) | PPARDPPARAPPARG | |
| SCHEMBL9979532 | 0.82 | PPARD (0.55) | PPARDPPARAPPARGUGCGITGB3 | |
| SCHEMBL9979578 | 0.79 | FFAR1 (0.43) | UGCGPOLBTDP1NPC1PKM | |
| SCHEMBL9979640 | 0.76 | PPARD (0.51) | PPARDPPARAPPARGPOLBSMN1; SMN2 | |
| SCHEMBL9979534 | 0.74 | FFAR1 (0.49) | PPARDPPARAPPARGUGCGNPC1 | |
| SCHEMBL9979490 | 0.73 | PPARD (0.53) | PPARDPPARAPPARG | |
| SCHEMBL9979488 | 0.73 | PPARD (0.53) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |