Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.31 |
| ▸ | TUBB | P07437 | 2/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769395 | 0.89 | ESR1 (0.50) | TSHRCYP3A4ESR1PDCD1ESR2 | |
| SCHEMBL6203868 | 0.89 | CHRNA7 (0.41) | TSHR | |
| SCHEMBL13283559 | 0.89 | TYR (0.41) | NPSR1GAA | |
| SCHEMBL17124666 | 0.89 | TSHR (0.36) | AOC3TSHRCYP3A4PPARGPPARD | |
| SCHEMBL6202340 | 0.87 | CYP1A2 (0.42) | NPSR1GAA | |
| SCHEMBL10186917 | 0.87 | IDO1 (0.31) | — | |
| SCHEMBL6205818 | 0.87 | CA12 (0.52) | AOC3TSHRSLC2A1ESR2 | |
| SCHEMBL20960412 | 0.87 | TDP1 (0.42) | TSHRCYP3A4BLMNFKB1PMP22 | |
| SCHEMBL6206391 | 0.87 | AOC3 (0.44) | AOC3GAA | |
| SCHEMBL2645634 | 0.87 | BLM (0.32) | TSHRBLMNPSR1GAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9978474-B2 | Conductive open frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-22 | — | — | US | disclosed |
| US-9978474-B2 | Conductive open frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-22 | — | — | US | disclosed |
| US-9598442-B2 | Crystallized hybrid solid having a three-dimensional DMOF-1-N3 organic-inorganic matrix and method for preparing the same | IFP Energies Nouvelles (FR) | 2017-03-21 | — | — | US | disclosed |
| US-20160247593-A1 | CONDUCTIVE OPEN FRAMEWORKS | UNITED STATES DEPARTMENT OF ENERGY | 2016-08-25 | — | — | US | disclosed |
| US-20160247593-A1 | CONDUCTIVE OPEN FRAMEWORKS | UNITED STATES DEPARTMENT OF ENERGY | 2016-08-25 | — | — | US | disclosed |
| US-9269473-B2 | Conductive open frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-23 | — | — | US | disclosed |
| US-9269473-B2 | Conductive open frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-23 | — | — | US | disclosed |
| US-20140081014-A1 | CONDUCTIVE OPEN FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-20 | — | — | US | disclosed |
| WO-2012082213-A2 | CONDUCTIVE OPEN FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160247593-A1 | CONDUCTIVE OPEN FRAMEWORKS | GJB2, OR10J3, EPCAM | AOC3 746/4885TSHR 4819/4885CYP3A4 2667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.