SCHEMBL9979948

SCHEMBL9979948

CC1CCC(c2ccc(F)c(F)c2)CC1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.52
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
HTR2B P41595 1/20 0.40
HCRTR2 O43614 2/20 0.37
USP30 Q70CQ3 1/20 0.37
KDM1A O60341 2/20 0.37
MAOB P27338 1/20 0.37
GRIA4 P48058 1/20 0.37
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
FASN P49327 1/20 0.36
USP5 P45974 2/20 0.36
HDAC6 Q9UBN7 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979956 0.94 ESR2 (0.47) ESR2HTR2AHTR2CHTR2BHCRTR2
SCHEMBL18503359 0.94 ESR2 (0.47) ESR2HTR2AHTR2CHTR2BHCRTR2
SCHEMBL9334585 0.90 ESR2 (0.43) ESR2HTR2AHTR2CHTR2BHCRTR2
SCHEMBL9334601 0.90 ESR2 (0.43) ESR2HTR2AHTR2CHTR2BHCRTR2
SCHEMBL2741542 0.90 ESR2 (0.43) ESR2HTR2AHTR2CHTR2BHCRTR2
SCHEMBL9334593 0.90 ESR2 (0.43) ESR2HTR2AHTR2CHTR2BHCRTR2
SCHEMBL14002670 0.90 ESR2 (0.43) ESR2HTR2AHTR2CHTR2BHCRTR2
SCHEMBL9334590 0.90 ESR2 (0.43) ESR2HTR2AHTR2CHTR2BHCRTR2
SCHEMBL10014224 0.90 ESR2 (0.43) ESR2HTR2AHTR2CHTR2BHCRTR2
SCHEMBL808710 0.89 HTR2A (0.46) ESR2HTR2AHTR2CHTR2BHCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9977294-B2 Liquid crystal display device INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2018-05-22 US disclosed
US-9977294-B2 Liquid crystal display device INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2018-05-22 US disclosed
EP-2977428-B1 POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DAINIPPON INK & CHEMICALS (JP) 2018-05-02 EP disclosed
EP-2690155-B1 LIQUID CRYSTAL ORIENTATION PROMOTER, LIQUID CRYSTAL COMPOSITION, MACROMOLECULAR MATERIAL, AND FILM FUJIFILM CORP (JP) 2017-10-25 EP disclosed
US-9765259-B2 Mesogenic compounds, liquid-crystalline media and components for high-frequency technology MERCK PATENT GMBH (DE) 2017-09-19 US disclosed
US-9765259-B2 Mesogenic compounds, liquid-crystalline media and components for high-frequency technology MERCK PATENT GMBH (DE) 2017-09-19 US disclosed
US-9670410-B2 Liquid crystal composition INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2017-06-06 US disclosed
US-9670410-B2 Liquid crystal composition INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2017-06-06 US disclosed
US-9664957-B2 Liquid crystal display device and method of driving the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2017-05-30 US disclosed
US-9664957-B2 Liquid crystal display device and method of driving the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2017-05-30 US disclosed
US-7303791-B2 Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices MERCK PATENT GMBH (DE) 2007-12-04 US disclosed
US-7303791-B2 Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices MERCK PATENT GMBH (DE) 2007-12-04 US disclosed
US-20070269614-A1 Containing at least two nitrile-free mesogenic compounds, one of which contains rings including a phenyl ring llinked by at least one -CF2O- group; electrooptical dispalys HECKMEIER MICHAEL 2007-11-22 US disclosed
US-7291367-B2 Liquid-crystalline compounds MERCK PATENT GMBH (DE) 2007-11-06 US disclosed
US-20070237907-A1 PHOTOSTABLE LIQUID-CRYSTALLINE MEDIUM MANABE ATSUTAKA 2007-10-11 US disclosed
US-7250198-B2 For electrooptical display MERCK PATENT GMBH (DE) 2007-07-31 US disclosed
US-7211302-B2 Photostable liquid crystalline medium MERCK PATENT GMBH (DE) 2007-05-01 US disclosed
US-7189440-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2007-03-13 US disclosed
US-20070034829-A1 liquid crystalline medium comprises at least one strongly polar two-ring compound containing at least one fluorine group and two benezne rings; liquid-crystalline medium has a dielectric relaxation frequency of more than 200 kHz at a temperature of 0 degrees C.; use in active matrix displays MERCK PATENT GMBH (DE) 2007-02-15 US disclosed
US-7175891-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2007-02-13 US disclosed