SCHEMBL10014224

SCHEMBL10014224

CC1CCC(CCC2CCC(c3ccc(F)c(F)c3)CC2)CC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 4/20 0.43
USP30 Q70CQ3 1/20 0.38
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
CYP2C9 P11712 2/20 0.37
HCRTR2 O43614 2/20 0.36
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
FASN P49327 1/20 0.35
OPRL1 P41146 2/20 0.35
USP5 P45974 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
CCR2 P41597 1/20 0.34
ESR1 P03372 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14002670 1.00 ESR2 (0.43) ESR2USP30HTR2AHTR2CHTR2B
SCHEMBL18503350 0.95 ESR2 (0.40) ESR2USP30HTR2AHTR2CHTR2B
SCHEMBL14228805 0.95 ESR2 (0.40) ESR2USP30HTR2AHTR2CHTR2B
SCHEMBL2741542 0.90 ESR2 (0.43) ESR2USP30HTR2AHTR2CHTR2B
SCHEMBL9979948 0.90 ESR2 (0.52) ESR2USP30HTR2AHTR2CHTR2B
SCHEMBL22031146 0.88 ESR2 (0.41) ESR2CYP2C9ALDH1A1LMNAMAPT
SCHEMBL7507561 0.87 CYP2C9 (0.50) ESR2USP30HTR2AHTR2CHTR2B
SCHEMBL7756551 0.87 CYP2C9 (0.40) ESR2USP30HTR2AHTR2CHTR2B
SCHEMBL7594396 0.87 CYP2C9 (0.50) ESR2USP30HTR2AHTR2CHTR2B
SCHEMBL7511645 0.87 CYP2C9 (0.40) ESR2USP30HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11193066-B2 Polymerizable compound and composition, liquid crystal composite, optical anisotropic body, liquid crystal display device and use thereof JNC CORPORATION (JP) 2021-12-07 US disclosed
EP-3725764-A1 POLYMERIZABLE COMPOUND HAVING METHOXYMETHYL ACRYLIC GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2020-10-21 EP disclosed
EP-3722278-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2020-10-14 EP disclosed
US-10759998-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display element JNC CORPORATION (JP) 2020-09-01 US disclosed
EP-3305774-B1 BENZOTHIOPHENE-CONTAINING LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2020-08-26 EP disclosed
EP-3495450-B1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2020-08-05 EP disclosed
EP-3406585-B1 TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2020-07-29 EP disclosed
US-10676669-B2 Compound having naphthalene ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-06-09 US disclosed
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 EP disclosed
EP-3495450-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2019-06-12 EP disclosed
US-8956550-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2015-02-17 US disclosed
US-20140293213-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2014-10-02 US disclosed
US-20140077131-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-03-20 US disclosed
US-20130208227-A1 SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
US-20130208227-A1 SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
WO-2012052100-A1 SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-04-26 WO disclosed
US-7714977-B2 Liquid crystal optical modulation element and optical head device ASAHI GLASS COMPANY, LIMITED (JP) 2010-05-11 US disclosed
US-7449222-B2 Liquid-crystalline medium MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-11-11 US disclosed
US-7449222-B2 Liquid-crystalline medium MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-11-11 US disclosed
US-20070104895-A1 LIQUID CRYSTAL OPTICAL MODULATION ELEMENT AND OPTICAL HEAD DEVICE ASAHI GLASS COMPANY, LIMITED (JP) 2007-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11193066-B2 Polymerizable compound and composition, liquid crystal composite, optical anisotropic body, liquid crystal display device and use thereof OCIAD2, PYM1, C1S ESR2 4495/4885USP30 3297/4885HTR2A 1375/4885
US-10676669-B2 Compound having naphthalene ring, liquid crystal composition and liquid crystal display device PYM1, CXCR1, CPNE4 ESR2 1913/4885USP30 4600/4885HTR2A 1866/4885
US-10759998-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display element SP1, SFXN3, SFXN1 ESR2 2449/4885USP30 4768/4885HTR2A 4086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.