SCHEMBL9979949

SCHEMBL9979949

CC1CCC(C2CCC(c3ccc(OC(F)(F)F)cc3)CC2)CC1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.47
EPHX2 P34913 5/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
KDM1A O60341 1/20 0.41
RCOR1 Q9UKL0 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HRH3 Q9Y5N1 1/20 0.39
MMP12 P39900 1/20 0.37
FAAH O00519 1/20 0.36
SLC6A4 P31645 3/20 0.35
SLC6A3 Q01959 1/20 0.35
TRPV1 Q8NER1 1/20 0.35
DHODH Q02127 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14229002 0.95 ESR2 (0.52) ESR2EPHX2L3MBTL1KDM1ARCOR1
SCHEMBL15180918 0.90 L3MBTL1 (0.48) ESR2EPHX2L3MBTL1KDM1ARCOR1
SCHEMBL15181143 0.88 ESR2 (0.45) ESR2EPHX2L3MBTL1KDM1ARCOR1
SCHEMBL9337076 0.88 ESR2 (0.45) ESR2EPHX2L3MBTL1KDM1ARCOR1
SCHEMBL9337087 0.88 ESR2 (0.45) ESR2EPHX2L3MBTL1KDM1ARCOR1
SCHEMBL9337061 0.88 ESR2 (0.45) ESR2EPHX2L3MBTL1KDM1ARCOR1
SCHEMBL8767731 0.87 MEN1 (0.44) EPHX2L3MBTL1KDM1ARCOR1MEN1
SCHEMBL9061651 0.86 ESR2 (0.44) ESR2EPHX2L3MBTL1KDM1ARCOR1
SCHEMBL14281234 0.86 ESR2 (0.44) ESR2EPHX2L3MBTL1KDM1ARCOR1
SCHEMBL9061646 0.86 ESR2 (0.44) ESR2EPHX2L3MBTL1KDM1ARCOR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 436 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
WO-2024017812-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-01-25 WO disclosed
US-20230383186-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-11-30 US disclosed
US-20230383186-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-11-30 US disclosed
EP-4279565-A2 THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME Merck Patent GmbH (DE) 2023-11-22 EP disclosed
EP-3810724-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2023-11-22 EP disclosed
EP-3980510-B1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2023-11-08 EP disclosed
EP-3679111-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2023-11-01 EP disclosed
US-20070237907-A1 PHOTOSTABLE LIQUID-CRYSTALLINE MEDIUM MANABE ATSUTAKA 2007-10-11 US disclosed
US-7270856-B2 Cyclobutane derivatives MERCK PATENT GMBH (DE) 2007-09-18 US disclosed
US-20070176144-A1 Liquid crystal composition for bistable liquid crystal devices MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2007-08-02 US disclosed
US-7250198-B2 For electrooptical display MERCK PATENT GMBH (DE) 2007-07-31 US disclosed
US-7211302-B2 Photostable liquid crystalline medium MERCK PATENT GMBH (DE) 2007-05-01 US disclosed
US-20070080325-A1 Liquid crystal composition for use in bistable liquid crystal devices MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-7189440-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2007-03-13 US disclosed
US-7179511-B2 For use in electro-optical displays MERCK PATENT GMBH (DE) 2007-02-20 US disclosed
US-20070034828-A1 Containing 3 directly connected rings: a fluorophenyl ring, a tetrahydropyran ring and either another tetrahydropyran ring or a 1,3-dioxane ring; electrooptical displays; MERCK PATENT GMBH (DE) 2007-02-15 US disclosed
US-20070001149-A1 Liquid-crystal medium containing monofluoroterphenyl compounds MERCK PATENT GMBH (DE) 2007-01-04 US disclosed