Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18354770 | 0.89 | PTGES2 (0.42) | CHKABACE1RARBPTGS2PDE3B | |
| SCHEMBL19820866 | 0.87 | RARB (0.46) | KDM1AHDAC1CHKABACE1RARB | |
| SCHEMBL13967517 | 0.86 | PTGS2 (0.46) | KDM1AHDAC1PTGS2PDE3BPDE3A | |
| SCHEMBL18503378 | 0.85 | BACE1 (0.46) | KDM1AHDAC1CHKABACE1RARB | |
| SCHEMBL17249597 | 0.85 | MAP2K4 (0.46) | KDM1AHDAC1CHKABACE1RARB | |
| SCHEMBL17615936 | 0.85 | RARB (0.41) | KDM1AHDAC1CHKABACE1RARB | |
| SCHEMBL10018702 | 0.84 | PTGS2 (0.48) | KDM1AHDAC1PTGS2PDE3BPDE3A | |
| SCHEMBL15854988 | 0.84 | RARB (0.40) | KDM1AHDAC1CHKABACE1RARB | |
| SCHEMBL19820863 | 0.84 | BACE1 (0.45) | KDM1AHDAC1CHKABACE1RARB | |
| SCHEMBL2810519 | 0.82 | PTGS1 (0.46) | BACE1RARBPTGS2PTGS1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168083-B2 | Electro-optical light control element, electro-optical display and control medium | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20100188630-A1 | ELECTRO-OPTICAL LIGHT CONTROL ELEMENT, ELECTRO-OPTICAL DISPLAY AND CONTROL MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-07-29 | — | — | US | disclosed |