Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13464891 | 0.86 | CYP3A4 (0.61) | CYP2C9CYP3A4KCNH2NR1I2ABCB11 | |
| SCHEMBL204507 | 0.82 | CYP2C9 (0.43) | CYP2C9CYP3A4KCNH2NR1I2ABCB11 | |
| SCHEMBL9980233 | 0.82 | CYP2C9 (0.43) | CYP2C9CYP3A4KCNH2NR1I2ABCB11 | |
| SCHEMBL9980192 | 0.81 | CYP3A4 (0.48) | CYP2C9CYP3A4KCNH2NR1I2ABCB11 | |
| SCHEMBL2756969 | 0.78 | CYP3A4 (0.61) | CYP2C9CYP3A4KCNH2NR1I2ABCB11 | |
| SCHEMBL2707990 | 0.78 | CYP3A4 (0.61) | CYP2C9CYP3A4KCNH2NR1I2ABCB11 | |
| SCHEMBL205945 | 0.78 | CYP3A4 (0.61) | CYP2C9CYP3A4KCNH2NR1I2ABCB11 | |
| SCHEMBL13070733 | 0.77 | CYP3A4 (0.59) | CYP2C9CYP3A4KCNH2NR1I2ABCB11 | |
| SCHEMBL9980194 | 0.76 | CYP3A4 (0.50) | CYP2C9CYP3A4KCNH2NR1I2ABCB11 | |
| SCHEMBL2756998 | 0.75 | CYP3A4 (0.59) | CYP2C9CYP3A4KCNH2NR1I2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157404-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157404-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | CYP2C9 3296/4885CYP3A4 1770/4885KCNH2 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.