Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 6/20 | 0.56 |
| ▸ | FLT3 | P36888 | 5/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.56 |
| ▸ | KIT | P10721 | 3/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1698789 | 0.87 | CSF1R (0.60) | CSF1RFLT3PDGFRBKITPDGFRA | |
| Hydrochloric Acid SCHEMBL1698737 | 0.79 | CSF1R (0.65) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL1698917 | 0.78 | CSF1R (0.66) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL1698956 | 0.76 | CSF1R (0.68) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9978910 | 0.75 | CSF1R (0.61) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL1698846 | 0.74 | FLT3 (0.72) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL12067861 | 0.73 | CSF1R (0.70) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL9978552 | 0.73 | CSF1R (0.59) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL1698727 | 0.73 | CSF1R (0.85) | CSF1RFLT3PDGFRBKITPDGFRA | |
| SCHEMBL1698832 | 0.72 | CSF1R (0.70) | CSF1RFLT3PDGFRBKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011150201-A2 | AZOLYL AMIDE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2011-12-01 | — | — | WO | claimed |
| WO-2011150201-A2 | AZOLYL AMIDE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011150201-A2 | AZOLYL AMIDE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2011-12-01 | — | — | WO | disclosed |