Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 3/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9982534 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP3A4THRBMAPK1METAP1 | |
| SCHEMBL9982296 | 0.91 | ALDH1A1 (0.44) | ALDH1A1CYP3A4THRBMAPK1METAP1 | |
| SCHEMBL9982102 | 0.90 | KDM1A (0.38) | ALDH1A1CYP3A4THRBMAPK1METAP1 | |
| SCHEMBL9981900 | 0.86 | ALDH1A1 (0.34) | ALDH1A1CYP3A4METAP1ACHECYP1A2 | |
| SCHEMBL9981588 | 0.86 | ALDH1A1 (0.34) | ALDH1A1CYP3A4METAP1ACHECYP1A2 | |
| SCHEMBL1739240 | 0.85 | GRM1 (0.31) | ALDH1A1CYP1A2HPGD | |
| SCHEMBL1739223 | 0.84 | HPGD (0.35) | HPGDHSD17B10 | |
| SCHEMBL9981832 | 0.84 | — | — | |
| SCHEMBL1740579 | 0.84 | HPGD (0.35) | HPGDHSD17B10 | |
| SCHEMBL9981735 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8211514-B2 | Reverse dispersion retardation film and liquid crystal display device using the same | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2012-07-03 | — | — | US | disclosed |