SCHEMBL9981949

SCHEMBL9981949

CC(C)Cc1ccc2cc3c(cc2c1)C1(CC2=CCC1C2)C(=O)CC3

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.34
MC4R P32245 1/20 0.30
BACE1 P56817 1/20 0.30
GRM1 Q13255 1/20 0.30
CTSD P07339 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9982303 1.00 ABL1 (0.34) ABL1MC4RBACE1GRM1CTSD
SCHEMBL1740484 0.91 BACE1 (0.34) ABL1MC4RBACE1
SCHEMBL1738041 0.89 BACE1 (0.34) ABL1MC4RBACE1
SCHEMBL9982498 0.89 CYP1A2 (0.35) GRM1
SCHEMBL9981289 0.89 CYP1A2 (0.35) GRM1
SCHEMBL9982286 0.87 MCHR1 (0.32) GRM1
SCHEMBL9981307 0.87 MCHR1 (0.32) GRM1
SCHEMBL1739223 0.85 HPGD (0.35)
SCHEMBL1740579 0.85 HPGD (0.35)
SCHEMBL9981204 0.85 CTSD (0.32) BACE1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211514-B2 Reverse dispersion retardation film and liquid crystal display device using the same JX NIPPON OIL & ENERGY CORPORATION (JP) 2012-07-03 US disclosed