Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.95 |
| ▸ | HPGD | P15428 | 6/20 | 0.95 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.95 |
| ▸ | CA12 | O43570 | 2/20 | 0.95 |
| ▸ | CA1 | P00915 | 2/20 | 0.95 |
| ▸ | CA2 | P00918 | 2/20 | 0.95 |
| ▸ | CA7 | P43166 | 2/20 | 0.95 |
| ▸ | CA9 | Q16790 | 2/20 | 0.95 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.95 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.95 |
| ▸ | CA4 | P22748 | 1/20 | 0.95 |
| ▸ | CA6 | P23280 | 1/20 | 0.95 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.95 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | G6PD | P11413 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL28120273 | 1.00 | ALDH1A1 (0.95) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL28650089 | 1.00 | ALDH1A1 (0.95) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1262212 | 1.00 | ALDH1A1 (0.95) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL536940 | 0.97 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL28814248 | 0.97 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL23795257 | 0.97 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL28007729 | 0.97 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL28047653 | 0.97 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1967 | 0.97 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29362663 | 0.97 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 15580 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122095059-A | Contains high content of C9Lubricant composition of di-substituted diphenylamine antioxidant | — | 2026-05-26 | — | — | CN | claimed |
| US-12624304-B2 | Lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2026-05-12 | — | — | US | claimed |
| WO-2026087620-A1 | LUBRICANT COMPOSITIONS CONTAINING HIGH C9 DISUBSTITUTED DIPHENYLAMINE ANTIOXIDANT CONTENT | INFINEUM INTERNATIONAL LIMITED (GB) | 2026-04-30 | — | — | WO | claimed |
| US-20260109910-A1 | Lubricant Compositions Containing High C9 Disubstituted Diphenylamine Antioxidant Content and Low Mono- and Tri-substituted Diphenylamine Antioxidant Content | INFINEUM INTERNATTIONAL LTD (GB) | 2026-04-23 | — | — | US | claimed |
| US-20260078315-A1 | LUBRICATING OIL COMPOSITIONS FOR HYBRID ENGINES AND METHODS OF USE AND TESTING THEREOF | INFINEUM INTERNATIONAL LIMITED | 2026-03-19 | — | — | US | claimed |
| CN-119307305-B | Alcohol-resistant low-viscosity lubricating oil composition and application thereof | 中国石油天然气股份有限公司 | 2026-02-27 | — | — | CN | claimed |
| US-20260028548-A1 | LUBRICANT COMPOSITIONS FOR DIRECT INJECTION ENGINES | THE LUBRIZOL CORPORATION (US) | 2026-01-29 | — | — | US | claimed |
| US-20260000741-A1 | METHOD OF AMELIORATING A PRO-INFLAMMATORY IMMUNOPHENOTYPE IN FARBER DISEASE SUBJECTS BY REPEATED ADMINISTRATION OF A RECOMBINANT HUMAN ACID CERAMIDASE | ACERAGEN INC (US) | 2026-01-01 | — | — | US | claimed |
| US-20250388765-A1 | Water Washable Ink or Paint | CRAYOLA LLC (US) | 2025-12-25 | — | — | US | claimed |
| EP-3810736-B1 | LUBRICATING OIL COMPOSITIONS | CHEVRON ORONITE CO (US) | 2025-12-24 | — | — | EP | claimed |
| US-4594382-A | Blend with a hydrated compound | THE DOW CHEMICAL COMPANY (US) | 1986-06-10 | — | — | US | claimed |
| EP-0174006-A2 | Antidiarrheal compositions and use thereof | Richardson-Vicks, Inc. (US) | 1986-03-12 | — | — | EP | claimed |
| EP-0094116-A2 | Therapeutic granules | THE PROCTER & GAMBLE COMPANY (US) | 1983-11-16 | — | — | EP | claimed |
| EP-0094117-A2 | Therapeutic granules | THE PROCTER & GAMBLE COMPANY (US) | 1983-11-16 | — | — | EP | claimed |
| EP-0094123-A2 | Therapeutic granules | THE PROCTER & GAMBLE COMPANY (US) | 1983-11-16 | — | — | EP | claimed |
| EP-0084910-A2 | High dropping-point lithium-complex grease having improved anti-noise properties | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-08-03 | — | — | EP | claimed |
| EP-0066918-A1 | Anti-inflammatory compositions exhibiting minimized gastric damage | THE PROCTER & GAMBLE COMPANY (US) | 1982-12-15 | — | — | EP | claimed |
| US-4287174-A | CONTAINING A QUATERNARY AMMONIUM CARBOXY ZWITTERIONIC COMPOUND AND AN ANTACID | THE PROCTOR & GAMBLE COMPANY (US) | 1981-09-01 | — | — | US | claimed |
| US-4256722-A | IMPREGNATING METAL OXIDES WITH DIVALENT METAL COMPOUNDS, FIRING | CORNING GLASS WORKS (US) | 1981-03-17 | — | — | US | claimed |
| EP-0004686-A2 | Anti-ulcer composition | THE PROCTER & GAMBLE COMPANY (US) | 1979-10-17 | — | — | EP | claimed |