Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.67 |
| ▸ | XDH | P47989 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998256 | 1.00 | ABCG2 (0.67) | ABCG2MAPTTNFRSF1AXDHMEN1 | |
| SCHEMBL997364 | 0.95 | ABCG2 (0.67) | ABCG2MAPTTNFRSF1AXDHMEN1 | |
| SCHEMBL997363 | 0.95 | ABCG2 (0.67) | ABCG2MAPTTNFRSF1AXDHMEN1 | |
| SCHEMBL997735 | 0.88 | MAPT (0.62) | ABCG2MAPTTNFRSF1AMEN1KMT2A | |
| SCHEMBL997734 | 0.88 | MAPT (0.62) | ABCG2MAPTTNFRSF1AMEN1KMT2A | |
| SCHEMBL997836 | 0.88 | ABCG2 (0.64) | ABCG2MAPTTNFRSF1AXDHMEN1 | |
| SCHEMBL997837 | 0.88 | ABCG2 (0.64) | ABCG2MAPTTNFRSF1AXDHMEN1 | |
| SCHEMBL996198 | 0.87 | PDE4A (0.64) | ABCG2MAPTTNFRSF1AMEN1KMT2A | |
| SCHEMBL996200 | 0.87 | PDE4A (0.64) | ABCG2MAPTTNFRSF1AMEN1KMT2A | |
| SCHEMBL996877 | 0.85 | ABCG2 (0.56) | ABCG2MAPTTNFRSF1AXDHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |